When you're synchronizing, nothing beats the convenience of ESTRUMATE prostaglandin:

  • 50-Dose and 10-Dose Bottles
  • 2-mL Dose for Heifers and Cows

The greater convenience of ESTRUMATE prostaglandin will save time and money, but when it comes to cattle reproduction, the important benefit of ESTRUMATE prostaglandin is potent performance.

Here's Why You Should Use Estrumate Prostaglandin

  • Half-Life for ESTRUMATE Prostaglandin is 3 Hours Versus a Few Minutes for Lutalyse1
  • ESTRUMATE prostaglandin lasts much longer1 than Lutalyse. The responsiveness of the corpus luteum to prostaglandin injection increases progressively during the early and the mid-stage of the estrous cycle.2
  • ESTRUMATE Prostaglandin is a More Potent Luteolytic Agent than Lutalyse3
  • ESTRUMATE Prostaglandin Quickly Reduces Progesterone Levels4 and Provides a Rapid Estrus Response5

Percent of Drug Not Cleared or Eliminated in Cattle by Time graphSee your veterinarian for ESTRUMATE prostaglandin

Footnotes:
1EMEA, The European Agency for the Evaluation of Medicinal Products. "Cloprostenol and R-Cloprostenol." Summary Report, April 1997. "Dinoprost." Summary Report, June 1997.
2Berardinelli, J.G., et al. "Effect of prostaglandin dosage and stage of estrous cycle on the estrous response and corpus luteum function in beef heifers." Theriogenology, 32:301-314, 1989.
3Martineau, R. "Dinoprost Versus Cloprostenol: Does Route of Injection Modulate Their Efficacy in Dairy Cattle?" The Bovine Practitioner, pp. 10-19, February 2003.
4Hayashi, K., et al. "Changes in Prostaglandin Secretion by the Regressing Bovine Corpus Luteum." Elsevier – Prostaglandins & Other Lipid Mediators. 70:339-349, 2003.
5Seguin, B., et al. "Cloprostenol and Dinoprost Tromenthamine in Experimental and Field Trials Treating Unobserved Estrus in Dairy Cows." The Bovine Practitioner, pp. 85-90, November 1985.

Estrumate Potent Performance

∗At 50 to 100 times the recommended dose, mild side effects may be detected in some cattle; these include increased uneasiness, slight frothing, and milk let-down.